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University of Rochester Laboratory Technician II, Biomedical Genetics - 227873 in Rochester, New York

Laboratory Technician II, Biomedical Genetics Job ID 227873

Location School of Medicine & Dentistry Full/Part Time Full-Time Favorite Job Regular/Temporary Regular Opening

Full Time 40 hours Grade 075 Dept of Biomedical Genetics




A Laboratory Technician II position is available at the University of Rochester Medical Center in the laboratories of Dr. Brian J. Altman (primary supervisor) and Dr. Stephano Mello (secondary supervisor). Dr. Altman’s laboratory studies the connections between the MYC cancer gene, altered metabolism in cancer, and circadian rhythms, the body’s natural 24-hour cycles. Circadian rhythm is an exciting and growing field that was recently recognized with the 2017 Nobel Prize in Medicine, and Dr. Altman hopes to contribute to our understanding of how and why circadian rhythms are disrupted in cancer.

The successful candidate will perform a share of lab housekeeping duties including record keeping, ordering and inventory for the Altman and Mello labs, assisting in training new lab members, and organization. The candidate will also be responsible for genotyping of mice from the Altman Lab animal colony, and assisting with animal experiments as needed. Finally, the candidate will assist with variety of experiments from cell culture and animal models to study the role of MYC and metabolic alterations in circadian rhythm control.

Ideally, the candidate should be familiar with a wide range of molecular biology and animal model techniques outlined below. Previous experience with R-language programming is desirable but not required. Finally, all members of the lab, regardless of position, are expected to read primary literature and make scientific contributions to the planning, execution, interpretation, and communication of experiments.

Initially, this individual will perform assignments with daily supervision, and over time, this individual will be expected develop some independence in planning and performing laboratory tests.

Procedures performed and equipment used :

Mouse handling and genotyping, analysis of large datasets using online tools, tissue culture, DNA and plasmid PCR and cloning, protein isolation and western blot, RNA isolation and quantitative PCR, microscopy (light and fluorescent).


Essential Tasks

% Effort


Performs lab housekeeping duties including inventory, organization, and ordering for the Altman Lab.



Performs lab housekeeping duties including inventory, organization, and ordering for the Mello Lab.



Maintains a mouse colony including husbandry, weaning, genotyping, and assisting with animal experiments.



Plans and performs, under supervision, a variety of cellular and molecular biology experiments and analyses on cell culture samples investigating cancer and circadian rhythm. Reads primary literature to understand bases for performed experiments. Performs basic computational experimentation using R programming, and troubleshoots simple code.



Performs other lab housekeeping duties for the Altman Lab including coordinating equipment maintenance and repair, and compliance with all University guidelines and policies.



Assists with preparing reports using defined methods and prescribed formats. Calculates and records results and observations. Prepares data for presentation or publication.



Additional duties as assigned.



  • Associate’s degree in Biology, Chemistry, Biochemistry, or Molecular Biology or equivalent combination of education and experience.

  • Candidates must have a demonstrated history of outstanding organization, time-management, and communication skills, including written communication.

  • Strong interpersonal skills and attention to detail.

  • Please include a list of skills that applicant is competent in.

  • Contact information for at least two references requested.

    Preferred Qualifications

  • Bachelors’ degree in Biology, Chemistry, Biochemistry, or Molecular Biology

    No involvement in the assessment, treatment or care of patients is involved with this work.

    How To Apply

All applicants must apply online.

EOE Minorities/Females/Protected Veterans/Disabled