University of Rochester Staff Scientist, Center for Oral Biology - 228324 in Rochester, New York
Staff Scientist, Center for Oral Biology Job ID 228324Location School of Medicine & Dentistry Full/Part Time Full-Time Favorite Job Regular/Temporary Temporary Opening
Full Time 40 hours Grade 055 Ctr for Oral Biology
THIS POSITION HAS AN END DATE OF 02/28/2023Schedule
9 AM-5 PMResponsibilities
THIS POSITION HAS AN END DATE OF 02/28/2023
Under the Principal Investigator’s (PI) guidance, independently direct and execute research projects studying regeneration and repair of tissue damage that occurs as a result of radiation therapy. Radiation treatment of head and neck cancer patients results in irreversible loss of salivary gland secretory acinar cells, and permanent dry mouth. Our data have revealed previously unrecognized regenerative capacity in irradiated human and mouse salivary glands, which involves cellular plasticity. This NIH-funded position is available to investigate the role of cellular plasticity and senescence in the response to injury and in regeneration, using genetically engineered mouse models, and human tissue, in combination with RNA Seq, and 3D in vitro cultures.
Supervision and Direction Exercised:
Undergraduates & graduate students
Machines and Equipment Used:
Computer and/or peripheral equipment, microscopes with imaging software, confocal microscope, microtome, cryostat, tissue processor, plate reader, thermal cyclers, irradiator, SARRP, incubators, centrifuges, autoclave.
Work independently on complex research project designated by the PI. Responsible for experimental design, acquisition of research materials, supplies, and equipment. Develop and modify experimental methods; select and implement procedures for data collection and handling. Design research projects, contribute to writing of research proposals, prepare regulatory documentation required for performance of research.
Write complete protocols for every experiment conducted, including purpose, experimental design, including detailed records of materials and methods used, experimental activities, and data storage. Utilize computer programs for data collection and statistical treatment of data. (25%%)
Contribute to aspects of larger ongoing research projects. Meet with collaborating team and contribute to project design and goals. Perform collection, analysis and evaluation of experimental data, and interpretion of results within the scope of the study. Contribute to the writing of research proposals and articles and prepares regulatory documentation required for the performance of research. (20%)
Prepare written reports on all phases of laboratory work involved in research projects. Contribute to the design, interpretation and final writing of research publications, thereby meeting expectations for co-authorship of scientific publications. Keep abreast of trends in the field by reading current research literature, abstracting scientific articles of value in the prosecution of research problems, and attend and present at scientific meetings, seminars and research conferences (15%)
Train and supervise undergraduate and early-stage graduate students. In cocollaboration with PI, design research projects/sub-projects, and supervise initial training, as well as progress of trainees with laboratory techniques and instrumentation procedures. Assist trainees with technical problems. (5%)
Complete and maintain annual compliance with University regulations and training for working with human tissue, working with rodents, laboratory safety training, and radiation safety training. (5%)
Other projects and duties as assigned. (5%)
Applicants must hold a Ph.D. in Cell and/or Molecular Biology, and have 2 or more years of postdoctoral experience using genetics, mouse models, cell culture, and molecular biology, as demonstrated through publications.
Applicants must have established experience and be willing to work with rodent models and husbandry, imaging, and protein and nucleic acid analysis, as well as previous training in statistical analysis.
Applicants must have excellent interpersonal, presentation (public speaking) and communication skills (including written communication), with proven ability to write scientific documents .
Applicants must have the ability to work independently, as well as the ability to work in a collaborative environment as part of a team.
Applicants should be able to multitask, have excellent organizational abilities, and pay close attention to detail.
How To Apply
All applicants must apply online.
EOE Minorities/Females/Protected Veterans/Disabled