Staff Scientist, SMD

Rochester, NY


The purpose of this position is to provide advanced, doctorate level scientific research for the Yao laboratory at Aab Cardiovascular Research Institute (CVRI) and Center for RNA Biology. A Staff Scientist position is available to investigate the molecular mechanisms underlying cardiac biology and heart disease to develop RNA-based therapeutics for treating human cardiac disorders and fibrosis-related diseases. Under general direction and with considerable latitude for exercising independent scientific judgment, this position provides direct research contributions to the laboratory by directing independent, complex research projects and/or major aspects of larger research projects. Provides guidance and/or directly supervises research technicians, graduate students, PhD, Post-Doctoral laboratory members, and technicians. May work as an independent researcher in a scientifically unique phase of research as part of a larger, complex project. Importantly, the candidate must be able to work well with others, and be a proficient communicator/instructor. The position requires an understanding of the scientific process that facilitates grant and manuscript generation, and a familiarity with the workings of the regulatory bodies of the University to allow for a productive lab environment.


  • With guidance from the Pl, designs and conducts complex experiments independently using adult mouse cardiomyocytes and cardiac fibroblasts, isolated mouse hearts and mouse models of cardiac diseases. Develops and installs protocols relevant to the research experiments and independently operates complex scientific equipment.

  • With guidance from the Pl, designs and conducts complex experiments independently using molecular biology, biochemistry, microscopy, and other approaches. Develops and installs protocols relevant to the research experiments and independently operates complex scientific equipment.

  • Independently analyzes and evaluates scientific experimental data and provides interpretation of results within scope of the study. Examines and assesses the importance of scientific findings in relation to the general field of cardiovascular research. Develops and modifies test methods; selects procedures for data collection and data handling. Develops, utilizes or adapts computer programs for statistical treatment and evaluation of scientific data.

  • Generates protocols and presentations relevant for the conduct of scientific research using Excel, GraphPad Prism, PowerPoint, and Adobe Illustrator software that include: purposes of study, design of experiments, list(s) of materials and methods use, the schedule of activities, results obtained and scientific interpretation and discussion. Contributes significantly to the writing of scientific research publications, grant applications and conference presentations, thereby meeting the requirements for co-authorship.

  • Keeps abreast of scientific trends and findings in the field(s) of interest by reading current research literature. Applies advanced scientific knowledge and expertise for the purpose of guiding and advising staff, trainees, colleagues and the Pl on scientific and technical problems within the scope of research and making recommendations for corrections. Creates and maintains a cohesive team- working environment. Provides scientific guidance to staff/trainees. Advises on technical problems and assists staff/trainees with special research projects.


  • Doctoral degree with a major course work in field of assignment required (molecular and cellular biology preferred)

  • Minimum of 2-5 years relevant postdoctoral training required

  • Ph.D. and/or MD with demonstrable expertise in molecular biology preferred

The University of Rochester is committed to fostering, cultivating, and preserving a culture of equity, diversity, and inclusion to advance the University’s mission to Learn, Discover, Heal, Create – and Make the World Ever Better. In support of our values and those of our society, the University is committed to not discriminating on the basis of age, color, disability, ethnicity, gender identity or expression, genetic information, marital status, military/veteran status, national origin, race, religion/creed, sex, sexual orientation, citizenship status, or any other status protected by law. This commitment extends to the administration of our policies, admissions, employment, access, and recruitment of candidates from underrepresented populations, veterans, and persons with disabilities consistent with these values and government contractor Affirmative Action obligations.

How To Apply

All applicants must apply online.

EOE Minorities/Females/Protected Veterans/Disabled

Pay Range

Pay Range: $60,431 - $84,603 Annually

The referenced pay range represents the minimum and maximum compensation for this job. Individual annual salaries/hourly rates will be set within the job’s compensation range, and will be determined by considering factors including, but not limited to, market data, education, experience, qualifications, expertise of the individual, and internal equity considerations.

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Location: School of Medicine & Dentistry
Full/Part Time: Full-Time