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University of Rochester Technical Assoc I (S) - 232559 in Rochester, New York

Technical Assoc I (S) Job ID 232559

Location School of Medicine & Dentistry Full/Part Time Full-Time Favorite Job Regular/Temporary Regular Opening

Full Time 40 hours Grade 051 Environmental Medicine

Schedule

8 AM-5 PM

Responsibilities

ESSENTIAL TASKS

Primary responsibilities are described below. Evening and weekend work will occasionally be required based upon experimental schedules and laboratory needs. Handling and use of laboratory animals, infectious agents, and chemicals will be required. Training in the safe handling of these agents is required, and will be provided. Exercise independent judgment and perform research activities independently with limited guidance from the principal investigator on adapting standard laboratory procedures to meet specific research-based goals. Ability to apply common sense approach to laboratory work, excellent time management, integration into an existing team, excellent interpersonal and communication skills are essential, including written communication. It is anticipated that the technician will be able to coordinate several projects simultaneously as well as train new laboratory members, including students, postdoctoral fellows and other technicians, on laboratory Standard Operating Proceudres (SOPs).

Experimental Research (75%):

Serve as technical associate for a Principal Investigator in the Department of Environmental Medicine. Work independently with only occasional suggestions to modify, vary or adapt standard laboratory procedures to perform research related activities to meet the specialized needs of the research projects of the Principal Investigator. Responsibilities will include:

  • Set up and conduct rodent inhalation exposures.This includes generation of metal nanoparticle atmospheres and their measurement (25%).

  • Develop and optimize new laboratory techniques including writing laboratory SOPs and training other technical staff and students on such SOPs. Perform scientific literature searches and utilize such literature to develop SOPs and advise the prinicipal investigator and/or her designee on appropriate technical approaches (10%).

  • Plan and oversee non-survival specimen collections from rodents. The technician will be required to independently utilize UCAR-approved and scientifically appropriate euthanasia methods followed by microdissection of the brain into regions of scientific interest (10%).

  • Conduct and oversee processing and analysis of collected specimens for immunohistological, biochemical, and molecular techniques including microscopy analysis, immunohistochemistry, histological analysis, Western blotting, ELISA, neurotransmitter quantification, and other techniques. The technican will also train other laboratory members (e.g., technical staff, students, etc.) on these techniques. Oversee the tissue processing for mass spectrometry (10%).

  • Supervise and train other members of the laboratory, including other technical staff, graduate students, undergraduates and work-study personnel (10%).

  • Assist Principal Investigator and other Laboratoy staff with planning and coordinating experimental timelines including scheduling other technical staff and students to complete experimental tasks (5%).

  • Strict adherence to written SOPs is required; as is detailed, daily record keeping (5%).

    Animal Care & Compliance (20%):

    Independently supervise and oversee large colonies of rodent breeding and maintenance. Duties will include oversight of preparation of experimental substance (e.g. drugs, environmental chemicals) administration; oversee the ordering, breeding, and euthanasia of rodents for laboratory use as well as detailed record keeping of such activities including UCAR and DLAM forms/reports. All animal work will be performed in compliance with DLAM and UCAR guidelines. The technician will communicate with DLAM staff in order to ensure the health of experimental research subjects. The technican will also coordinate with UCAR for annual and ad-hoc inspections to ensure compliance with all UCAR polices. It is anticipated that the technican will provide guidance and train and supervise other laboratory members (e.g. students, technicians, etc.) to complete these duties.

    Laboratory & Other Meetings (5%):

    Participate and contribute to regularly-scheduled laboratory meetings. Provide a verbal account of progress on lab-specific goals, including experimental progress on research activities, as well as reporting of lab members’ compliance with Federal, State, and University regulations for use of laboratory animals, radioactivity, hazardous materials, and general laboratory health and safety as needed. Communicate with collaborators and university core facilities (e.g. inhalation facility, Center for Visual Science, histology core, microscopy core, behavioral core, etc.) via in-person meetings, email, and phone calls to coordinate research activities.

    Other projects and job duties as assigned.

    *Education/Experience (minimum required):

  • Bachelor’s Degree in chemistry, neuroscience or toxicology, or related scientific discipline and at least 1+ years of experience in related techniques or equivalent combination of education and experience.

  • Operational understanding of basic laboratory equipment, including the ability to make solutions, use centrifuges, and accurately operate micropipettors is required, as are mathematical skills including basic algebra and the ability to use scientific notation.

  • Experience with Microsoft Office software including Powerpoint, Excel, and Word..

  • Excellent organizational skills, ability to use good judgement, and attention to detail.

  • Strong intepersonal skills and the ability to communicate effectively, including in writing.

  • Must be able to work some evenings and weekends to conduct experiments.

    DESIRED QUALIFICATIONS

    Experiential knowledge of the basic workings of a research laboratory and common equipment including general knowledge of chemistry and biology. Candidates with prior experience in inhalational exposures, handling research animals, rodent behavioral techniques, histology, ELISA, HPLC, and Western Blots are highly desired.

    License/Certification Required: None

    NOTE: This document describes typical duties and responsibilities and is not intended to limit management from assigning other work as required.

    How To Apply

All applicants must apply online.

EOE Minorities/Females/Protected Veterans/Disabled

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